The Misuse of Over-the-Counter NSAIDs

Over-the-counter nonsteroidal anti-inflammatory drugs (NSAIDs) are some of the most frequently used analgesics. The misuse of these medications occurs frequently and often without the patient’s realization. Inappropriate use can cause acute NSAID overdoses or contribute to serious adverse effects. Health care providers continue to play an important role in emphasizing the safe use of these medications. This article examines the impacts of NSAID misuse in our society and how health care professionals can help address these issues

Enabling prosperity: success factors in Indigenous economic development

Public discussion about ‘closing the gap’ between Indigenous and non-Indigenous Australians tends to focus on measures such as life expectancy, child mortality, early childhood education, literacy and numeracy, and employment.  These are, rightly, essential markers of health and well-being for all people, and for decades they have provided evidence that Australia’s health and social systems have not met the needs of Indigenous Australians. However, there is another story, one that focuses on the measures of success, as evident in the many thriving Indigenous businesses and corporations around the country.  Across Australia, there is a growing story of economic security and success, in which Indigenous Australians are creating enterprises combining sound business principles with strong cultural and social foundations for the benefit of individuals, families and communities. Urbis was commissioned by Westpac to undertake research into Indigenous business development, to provide an evidence base to support the work of the Empowered Communities group. The report, Enabling Prosperity: Success Factors in Indigenous Economic Development, suggests that these factors are much the same as for any other businesses: human capital, access to capital and markets, infrastructure, location and an authorising environment created through government policy and regulation. In practice, businesses succeed because of more than one factor, and multiple factors can strengthen the capacity of a business to grow and develop.  For instance, access to capital often relies on the development of successful partnerships, while ownership of land and resources requires human capital to realise its potential. Indigenous culture can be both a support and a resource. Individual attitude and vision are also essential ingredients in business success, while government plays an important role in ensuring the regulatory environment enables rather than hinders business efforts. Much can be learned by examining successful Indigenous businesses both in Australia and internationally. Businesses are the key driver for wealth creation, helping to provide job opportunities and improve social and economic conditions. Fostering business success, therefore, has the potential to increase employment, improve living standards, and contribute to stable and nurturing communities. Current government policy frameworks, such as the Indigenous Economic Development Strategy, are largely focused on increasing education and training and generating opportunities for private sector employment and enterprise.  This is important. Just as important is the contribution that successful community or non-profit enterprises can make in providing employment, generating business investment for growth, building partnerships and demonstrating positive role models. The Empowered Communities group is such a national initiative. Formed in 2013, the group brings together Indigenous leaders from eight communities across Australia and seeks to strengthen Indigenous individuals and communities through a range of activities (see https://empoweredcomms.wordpress.com for more information). Strategies that strengthen both individual and community business initiatives will help to ensure that more Indigenous Australians have the opportunity to live successful and productive lives.  Everyone has a contribution to make in this regard. Governments can create an enabling regulatory environment. Banks can enable access to capital. Local chambers of commerce can foster business development through support and networks for new entrepreneurs. Communities and individuals can purchase goods and services from Indigenous businesses. Building a strong and vibrant Indigenous business and social enterprise sector can then contribute to improving many of the health and social indicators, such as improving nutrition and healthy lifestyle choices, and increasing employment and education.  Efforts to improve Indigenous outcomes really are everyone’s business

Women with early maltreatment experience show increased resting-state functional connectivity in the theory of mind (ToM) network

Background: Experience of childhood maltreatment significantly increases the risk for the development of psychopathology and is associated with impairments in socio-cognitive skills including theory-of-mind (ToM). In turn, neural alterations in ToM processing might then influence future interpersonal interaction and social-emotional understanding. Objective: To assess resting-state activity in the theory-of-mind network in traumatized and non-traumatized persons. Methods: Thirty-five women with a history of childhood maltreatment and 31 unaffected women completed a resting-state scan and a ToM localizer task. The peak coordinates from the localizer were used as the seed regions for the resting-state functional connectivity (RSFC) analyses (temporo-parietal junction, dorsomedial prefrontal cortex, middle temporal gyrus and precuneus). Results: Child abuse was associated with increased RSFC between various ToM regions including the precuneus and the brainstem suggesting altered hierarchical processing in ToM regions. Number of types of abuse was driving the effect for the temporo-parietal junction and the brainstem, while the severity of abuse was linked to increased RSFC between the middle temporal gyrus and the frontal cortex. Post-hoc analyses of brainstem regions indicated the involvement of the serotonergic system (dorsal raphe). Conclusions: The data indicate a lasting impact of childhood maltreatment on the neural networks involved in social information processing that are integral to understanding others' emotional states. Indeed, such altered neural networks may account for some of the interpersonal difficulties victims of childhood maltreatment experience

Intersectional anti racist advocacy practice in healthcare organizations

Health care organizations, like individuals, can evolve to become antiracist and promote racial equity within and beyond the organization. In this brief article, we introduce an intersectional antiracist advocacy practice framework applicable to health care organizations that seek restorative and transformative change, as well as participation in social and economic justice action. Becoming an antiracist organization requires an acknowledgment that no organization is impervious to racist and other oppressive ideologies. Organizations can then begin to interrogate, interrupt, and address how racism permeates agency policies, procedures, and culture. The implementation of an intersectional antiracist advocacy practice framework within organizations involves a multifaceted approach, including both internal and external practices. Internally facing practices include providing mandatory antiracist trainings to all employees; promoting a representative and equitable workplace; and developing an organizational power structure based on inclusion, transparency, and accountability. Externally facing practices include fostering nonexploitative, reciprocal community partnerships; contributing to social and economic justice movements; and demonstrating transparency and accountability for the negative impact of operations in Black, Indigenous, and People of Color (BIPOC) communities and lands. We conclude with key questions for health care organizations to consider in regard to their racial equity efforts, specifically around organizational readiness, risk tolerance, and long-term commitment

Sophomore Recital: Andrew Hudson, Tenor; Sara Hoffee, Piano; February 25, 2010

Kemp Recital HallFebruary 28, 2010Sunday Afternoon4:00 p.m

“Render a service worthy of me”: A qualitative study of factors influencing access to LGBTQ-specific health services

For a half-century, LGBTQ-specific health services have sought to address the unmet health care needs of LGBTQ people in the U.S. However, there is a dearth of research examining factors that influence LGBTQ care-seekers’ reasons for choosing LGBTQ-specific services and their experiences accessing care. This interview-based study explored factors that facilitate and inhibit access to LGBTQ-specific health services among a sample of 40 LGBTQ adults in a major U.S. city. Using framework analysis, emergent themes were organized into supply- and demand side factors, guided by Levesque et al.’s (2013) framework for patient-centered health care access. Supply-side factors included provider empathy and affirmation, provider knowledge, comprehensive care, and provider based stigma. Demand-side factors included care-seeker\u27s willingness for self-disclosure, care-seeker beliefs placing primacy on health needs over LGBTQ identities, contentment with general providers, a lack of knowledge for service identification, and perceptions of ability to pay. Social aspects of care seeking were also identified, including desires for social belonging, collective self-esteem, and community solidarity. Findings suggest opportunities to enhance the fit between health care policy, LGBTQ-specific provider characteristics, and care-seeker needs, particularly for multiply marginalized LGBTQ communitie

Operationalizing intersectionality in social work research: Approaches and limitations

Despite intersectionality’s relevance to social work, scholars have raised concerns that its misguided applications place it “in danger of being co-opted, depoliticized, and diluted.” This scoping review examined the use of intersectionality in empirical social work research, specific to the extent, contexts, and degree of responsibility with which it has been applied. Using the search term convention [“social work” OR “social services”] AND [“intersectional” OR “intersectionality”], 22 databases were searched for peer-reviewed research published between 2009 and 2019, yielding 153 articles. The 33 studies meeting inclusion criteria were examined according to two frameworks: (1) typologies for intersectional conceptual approach and (2) intersectionality responsible use guidelines (RUG). Most studies used an intracategorical approach (n ¼ 24), while fewer used an intercategorical (n ¼ 7) or a mixed intra- and intercategorical approach (n ¼ 2). On average, studies met approximately half of the RUG. Studies most frequently (n ¼ 29) aligned with the guideline “Recommend ways to promote positive social transformation and justice through research, teaching, and practice.” Studies least frequently (n ¼ 3) conformed to the guideline “Credits Black feminist activist roots of intersectionality.” Responsible stewardship is recommended to address power in knowledge production, researcher positionalities, and social justice action

The Genetic Signature of Perineuronal Oligodendrocytes

Oligodendrocytes in the central nervous system can be categorized as precursors, myelin-forming, and non-myelinating perineuronal cells. The function of perineuronal oligodendrocytes is unknown; it was proposed that following injury, they may remyelinate denuded axons. We investigated these cells' potential. A combination of cell-specific tags, microarray technology and bioinformatics tools to identify gene expression differences between these subpopulations allowed us to capture the genetic signature of perineuronal oligodendrocytes. Here we report that perineuronal oligodendrocytes are configured for a dual role. As cells that embrace neuronal somata, they integrate a repertoire of transcripts designed to create their own code for communicating with neurons. But they maintain a reservoir of untranslated transcripts encoding the major myelin proteins for - we speculate - a demyelinating episode. We posit that the signature molecules, PDGFR-[alpha][beta] cytokine PDGF-CC, and transcription factor Pea3, used - among others - to define the non-myelinating phenotype, may be critical for mounting a myelinating programme during demyelination. Harnessing this capability is of therapeutic value for diseases such as multiple sclerosis. This is the first molecular characterization of an elusive neural cell

Fostering Insight and Collaboration in Long-Term Healthcare through Collection and Visualization of Qualitative Healthcare Data

The Care and Condition Monitor (CCM) is a tablet-based, networked visual analytics tool for collecting, structuring and analyzing informal and qualitative healthcare data. Building off research into application usability and best practices for communicating complex information, CCM illustrates how visual analytics tools coupled with social communication within teams of caregivers enables capturing of longitudinal informal data that would otherwise go unrecorded. This expanded scope of information can support medical decision making by making it possible to analyze informal and qualitative health care data,creating a multi-dimensional holistic picture of a person‟s health care and condition over time

Women with early maltreatment experience show increased resting-state functional connectivity in the theory of mind (ToM) network.

Background: Experience of childhood maltreatment significantly increases the risk for the development of psychopathology and is associated with impairments in socio-cognitive skills including theory-of-mind (ToM). In turn, neural alterations in ToM processing might then influence future interpersonal interaction and social-emotional understanding. Objective: To assess resting-state activity in the theory-of-mind network in traumatized and non-traumatized persons. Methods: Thirty-five women with a history of childhood maltreatment and 31 unaffected women completed a resting-state scan and a ToM localizer task. The peak coordinates from the localizer were used as the seed regions for the resting-state functional connectivity (RSFC) analyses (temporo-parietal junction, dorsomedial prefrontal cortex, middle temporal gyrus and precuneus). Results: Child abuse was associated with increased RSFC between various ToM regions including the precuneus and the brainstem suggesting altered hierarchical processing in ToM regions. Number of types of abuse was driving the effect for the temporo-parietal junction and the brainstem, while the severity of abuse was linked to increased RSFC between the middle temporal gyrus and the frontal cortex. Post-hoc analyses of brainstem regions indicated the involvement of the serotonergic system (dorsal raphe). Conclusions: The data indicate a lasting impact of childhood maltreatment on the neural networks involved in social information processing that are integral to understanding others' emotional states. Indeed, such altered neural networks may account for some of the interpersonal difficulties victims of childhood maltreatment experience